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Plant and animal GSTs play a key role in conjugating GSH with such endogenously produced electrophiles, which results in their detoxification (Bartling et al., 1993

Bergenin decreases the morphine-induced physical dependence via antioxidative activity in mice

[DOI] [PMC free article] [PubMed] [Google Scholar] 41.Ma X., Chang Y., Zhang Y., Muhammad I., Shi C., Li R., Li C., Li Z., Lin Y., Han Q., et al

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In the yeast enzyme, an active site Mg 2+ , orients the glutamate -carboxylate for attack on the -phosphate of ATP, which is positioned by a second Mg 2+ and an active site lysine